Standard BioTools

Standard BioTools (formerly Fluidigm) is a life science company that provides high-dimensional biology platforms enabling deep phenotyping of single cells and tissues. The company's Helios mass cytometer, based on Cytometry by Time-Of-Flight (CyTOF) technology, uses heavy metal isotope-tagged antibodies detected by mass spectrometry rather than fluorescence, eliminating spectral overlap and enabling simultaneous measurement of more than 50 protein markers per cell. This makes CyTOF uniquely powerful for immunophenotyping, distinguishing rare immune cell subsets, and systems immunology studies. The IMC (Imaging Mass Cytometry) platform, sold as Hyperion, extends this capability to tissue sections, providing spatial proteomic data at subcellular resolution. Researchers in oncology, immunology, and stem cell biology use Standard BioTools platforms to map complex cellular ecosystems in human disease. The X9 real-time PCR system enables highly parallel targeted gene expression analysis through microfluidic chip technology, allowing up to 9,216 individual qPCR reactions per chip run. Standard BioTools also offers the Biomark HD for digital PCR and gene expression profiling at microfluidic scale, and a range of panel-ready antibody kits for standardized mass cytometry workflows. Their deep integration between metal-labeled panels and instrument platforms provides researchers with validated end-to-end workflows for cell therapy characterization, vaccine immunogenicity studies, and biomarker discovery.