Miltenyi Biotec

Miltenyi Biotec is a global biotechnology company founded in 1989 in Bergisch Gladbach, Germany, that develops and manufactures technologies for cell biology research, cell therapy manufacturing, and clinical translation. The company's MACS (Magnetic-Activated Cell Sorting) technology is the gold standard for magnetic cell isolation, using superparamagnetic microbeads conjugated to antibodies to selectively deplete or positively select cell populations from complex biological samples. Researchers in immunology, hematology, and stem cell biology rely on MACS columns and the AutoMACS Pro automated system for high-purity cell isolations from blood, bone marrow, lymph nodes, and solid tissues. Miltenyi's CliniMACS and CliniMACS Prodigy systems extend these capabilities to GMP-grade cell processing for clinical CAR-T cell manufacturing, regulatory T cell therapies, and stem cell transplantation products. The GentleMACS tissue dissociation instruments and enzyme kits have become the standard method for generating single-cell suspensions from solid tumors and other tissues for downstream single-cell analysis. Miltenyi's MACSQuant flow cytometers and REAfinity recombinant antibodies address the need for standardized, lot-independent immunophenotyping reagents. Their Tumor Dissociation Kit and subsequent MACS panel workflows create a validated pipeline from tissue biopsy to characterized single-cell suspension that is widely used in academic cancer research and pharmaceutical oncology.