# Charles River Laboratories

> Charles River Laboratories is a Wilmington, Massachusetts-based contract research organization founded in 1947 that provides comprehensive drug discovery, preclinical, and clinical laboratory services to pharmaceutical, biotechnology, and government research clients. The company is the world's largest commercial supplier of research-grade laboratory animals, providing rats, mice, guinea pigs, rabbits, and non-human primates produced under strict genetic and health standards for academic biomedical research, pharmaceutical pharmacology studies, and regulatory toxicology assessments. Charles River's research models include specialized genetically engineered strains, inbred reference strains, and outbred stock that serve as the foundation for thousands of published studies annually. Their Safety Assessment division conducts GLP-compliant toxicology studies including general toxicology, genetic toxicology, reproductive and developmental toxicology, and carcinogenicity assessments required for Investigational New Drug (IND) applications to the FDA. The Discovery Services division offers integrated drug discovery services from target validation and assay development through lead optimization and candidate selection, enabling academic spinouts and small biotechs to access CRO capabilities without building their own infrastructure. Charles River's Biologics Testing Solutions division handles lot release, quality control, and adventitious agent testing for biologic drug manufacturers. Their Microbial Solutions business provides endotoxin testing, mycoplasma testing, and environmental monitoring services critical to pharmaceutical manufacturing research. Their recent acquisitions in cell therapy quality testing and gene therapy vector characterization expand their relevance to advanced therapy development.

*Source: [https://selltoscientists.com/companies/charles-river-laboratories/](https://selltoscientists.com/companies/charles-river-laboratories/)*

**Industry:** Drug Discovery & Preclinical Services
**R&D spend:** $245M
**Academic collaborations:** 1650
**Patents:** 1,800

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